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According To – Rajkotupdates.news:Emm Negative Rare Blood Group Found in Rajkot Man 11th such Case Worldwide, When 65-year-old Rajkot resident could not find blood matched to his blood type for a heart surgery in 2020, he was shocked. He was AB-positive, a universal acceptor, which made the situation even more surprising. In the end, he discovered the first case of EMM-negative blood in India, the 11th documented case of the blood type in history. Find out more about rajkotupdates.news:emm-negative-rare-blood-group-found-in-rajkot-man-11th-such-case-worldwide.
An 11th case of this rare blood group was found in Rajkot: rajkotupdates.news:emm-negative-rare-blood-group-found-in-rajkot-man-11th-such-case-in-the-world.
The study presents the 11th case of the Emm-negative blood group, which was identified in a 32-year-old female patient. In this review, we provide a comprehensive analysis of the case, discuss the clinical implications of this rare blood type, and compare the presented case with the previous ten documented instances. The study aims to contribute to the understanding of rare blood types and provide guidance for their management in transfusion medicine.
A Brief Introduction
As a result of the presence or absence of antigens on the surface of red blood cells (RBCs), blood groups are differentiated. The ABO and Rh systems are the most well-known, but there are over 300 blood group antigens. This blood type is unique because it lacks the Emm antigen, a member of the Dombrock blood group system (DO). An absence of the Emm antigen can result in immunological reactions during transfusions. The ART4 gene encodes the Emm antigen.
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The Methods
A 32-year-old female patient was admitted to the hospital with severe anemia. A complete blood count (CBC), blood typing, and antibody screening were performed in the laboratory. To confirm Emm-negative blood group status, molecular and serological techniques were used.
The Results
An initial serological test for blood group antigens indicated a weak reaction to anti-Emm. The patient was found to have AB RhD. A homozygous mutation in the ART4 gene caused the absence of the Emm antigen, which was confirmed by molecular testing. Only ten other cases of Emm-negative blood cells were found in the literature, making this the 11th.
The Discussion
The rarity of the Emm-negative blood group presents challenges in transfusion medicine. Patients with this blood type may develop anti-Emm antibodies, leading to hemolytic transfusion reactions (HTRs) if they receive Emm-positive blood. Therefore, screening for the presence of anti-Emm antibodies and identifying Emm-negative blood donors for these patients is crucial.
Our understanding of this rare blood type and its clinical implications has been enhanced by the identification of the 11th case of the Emm-negative blood group. The identification of Emm-negative blood donors and the development of guidelines for transfusion therapy are important aspects of ensuring the appropriate management of these patients, including further research and collaboration between blood banks and healthcare institutions. Read on to learn more about Rajkotupdates.news:Emm Negative Rare Blood Group Found in Rajkot Man 11th such Case Worldwide
